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Planning and self-assessment

Biomarker Test Planner

A test list to take to a clinician, ordered by how much the result would actually change a decision.

Formula lll-test-planner-1.0.011 sources6 stated limitationsClinical estimate

This page has no named medical reviewer on file. The equation it implements is published and cited below, but the page itself has not been signed off by a member of the review board, and we do not present it as if it had been.

Enter your numbers

21 questions. Questions that only apply to some people appear once your earlier answers decide that they do.

From your health data

3 of these questions can be answered from lab results and device data you have already connected: Age, Sex at birth, Your 10-year cardiovascular risk, if you know it. Connect them once in your member account and they arrive here pre-filled and labelled as coming from your health data — and you can always type over the value.

Set up health data in your member account

This public page never reads your health data. Pre-filling happens inside the signed-in app, which is a separate, access-controlled surface.

Biomarker Test Planner inputs
Sex at birthFrom your health data — connect to fill this automatically

Used because the reference data and published equations are sex-specific. If your sex at birth differs from your gender, the equations were derived on sex-at-birth cohorts.

The plan is filled from the cheapest high-value tests upwards.

From your health data — connect to fill this automatically

From the heart age calculator. Used to decide whether coronary calcium scoring is in the guideline-supported band.

Nothing you type is stored unless you are signed in and ask us to save it.

How this is calculated

Formula version lll-test-planner-1.0.0

Each test in the catalogue carries a tier, a rationale, an indicative US self-pay price range, the guideline position that supports it and, where one exists, the screening-body caution against it. Tests whose inclusion predicate matches the member's age, sex, goals and conditions are sorted essential first and cheapest first within a tier, then added to the plan while their low-end price still fits the stated budget; anything that does not fit is reported as deferred rather than dropped silently. Coronary calcium is gated on age and, where a ten-year risk is known, on the intermediate or selected-borderline risk band the guideline specifies.

What it cannot do

  • Prices are US direct-to-consumer list prices captured on one day and vary up to five-fold between vendors for the same test. They are not insurance rates.
  • No sourced price is held for urine albumin-to-creatinine ratio, so it is excluded from totals.
  • The catalogue is a curated shortlist, not an exhaustive panel, and it deliberately omits tests with no plausible action attached.
  • Guideline positions change. The US cholesterol guideline was updated in March 2026 and the ESC/EAS Lp(a) threshold moved in 2025; the positions quoted are the ones cited above and should be reviewed at each formula version.
  • Budget filling by cheapest-first inside a tier is an editorial rule, not an evidence-based prioritisation.
  • Symptoms are not properly modelled. A symptomatic person needs a clinician, not a planner.

Sources

  1. Grundy SM et al. 2018 AHA/ACC Guideline on the Management of Blood Cholesterol. Circulation 2019;139(25):e1082-e1143DOI 10.1161/CIR.0000000000000625 (opens in a new tab)PMID 30586774 (opens in a new tab)
  2. Arnett DK et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease. Circulation 2019;140(11):e596-e646DOI 10.1161/CIR.0000000000000678 (opens in a new tab)PMID 30879355 (opens in a new tab)
  3. Mach F et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias. Eur Heart J 2020;41(1):111-188DOI 10.1093/eurheartj/ehz455 (opens in a new tab)PMID 31504418 (opens in a new tab)
  4. Mach F et al. 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias. Eur Heart J 2025DOI 10.1093/eurheartj/ehaf190 (opens in a new tab)
  5. Kronenberg F et al. Lipoprotein(a): EAS consensus statement. Eur Heart J 2022;43(39):3925-3946DOI 10.1093/eurheartj/ehac361 (opens in a new tab)PMID 36036785 (opens in a new tab)
  6. American Diabetes Association. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2026. Diabetes Care 2026;49(Suppl 1):S27-S49
  7. USPSTF. Screening for Prediabetes and Type 2 Diabetes. JAMA 2021;326(8):736-743DOI 10.1001/jama.2021.12531 (opens in a new tab)PMID 34427594 (opens in a new tab)
  8. USPSTF. Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors. JAMA 2018;320(3):272-280DOI 10.1001/jama.2018.8359 (opens in a new tab)PMID 29998297 (opens in a new tab)
  9. USPSTF. Screening for Vitamin D Deficiency in Adults. JAMA 2021;325(14):1436-1442DOI 10.1001/jama.2021.3069 (opens in a new tab)PMID 33847711 (opens in a new tab)
  10. USPSTF. Screening for Thyroid Dysfunction. Ann Intern Med 2015;162(9):641-650DOI 10.7326/M15-0483 (opens in a new tab)PMID 25798805 (opens in a new tab)
  11. Demay MB et al. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2024;109(8):1907-1947DOI 10.1210/clinem/dgae290 (opens in a new tab)PMID 38828931 (opens in a new tab)

The formula version is pinned so that a result you saved or shared can be reproduced. When we change a coefficient, the version changes and old results stay attributed to the version that produced them.

Questions people ask

Why does it not just list everything?
Because a test that will not change what you do is a cost and a source of anxiety, not information. Ordering fifty markers guarantees several will be outside a reference range by chance alone, and chasing those does harm.
Can I order these myself?
In some markets, yes. That does not make it a good idea without someone to interpret them with you — a result you cannot act on is worse than no result. The labs directory lists where the tests can be obtained.