Every intervention, graded
0 interventions, each graded per outcome. A grade is never a single verdict on a molecule — it is a verdict on a molecule for a specific outcome in a specific population, which is why one intervention can be an A for one thing and an F for another.
What the grades mean
How we grade evidence
- Evidence grade: Strong evidence
- Consistent findings from multiple well-conducted human trials or systematic reviews.
- Evidence grade: Moderate evidence
- Reasonable human evidence, but with limitations in size, duration or consistency.
- Evidence grade: Limited evidence
- Early or mixed human evidence; effects are small, uncertain or narrow.
- Evidence grade: Weak evidence
- Mostly preclinical, mechanistic or anecdotal support; no reliable human outcome data.
- Evidence grade: No credible evidence
- Claims are contradicted by the available human evidence.
- Evidence grade: Evidence of harm
- Documented risk of harm. Do not use without qualified medical supervision.
- Evidence grade: Insufficient evidence
- Too little trustworthy evidence exists to grade this yet.
No interventions match these filters. Clear filters
Grade distribution
Most things people take are not grade A. That is the honest picture, and we publish it rather than hiding it behind a curated list.
- Evidence grade: Strong evidence0interventions
- Evidence grade: Moderate evidence0interventions
- Evidence grade: Limited evidence0interventions
- Evidence grade: Weak evidence0interventions
- Evidence grade: No credible evidence0interventions
- Evidence grade: Evidence of harm0interventions
- Evidence grade: Insufficient evidence0interventions